Package that calculates a truncated exact test for two-stage case-control studies for rare genetic variants. The first stage is for screening rare variants in only cases. If the number of case-carriers of any rare variants exceeds a user-specified threshold, then additional cases and controls are genotyped for the detected variants and carrier status of these variants are compared for all cases and controls in the second stage.
- Jason Sinnwell (primary contact)
- Dan Schaid
Page last modified: July 23, 2018